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Real Madrid dropped to second place in La Liga with a 1-0 defeat at 10th-placed Levante in a match that saw Eden Hazard limp off with an injury.
Barcelona wonderkid Ansu Fati, 17, scored twice to lead his side to a 2-1 win at home to Levante, the youngest ever to score a brace in La Liga.
Atletico Madrid made it three La Liga wins in a row by beating Levante 2-1 at home on Saturday to climb up to third in the standings.
A Spanish court has cleared 41 people and Real Zaragoza of match-fixing charges in a Liga fixture between Levante and Real Zaragoza in 2011.
Barcelona could lose top spot in La Liga later on Saturday after Levante scored three times in seven minutes to come from behind and win 3-1.
Sevilla striker Luuk de Jong scored his first goal for the club to give them a deserved 1-0 win at home to Levante.
Karim Benzema scored twice as Real Madrid stumbled to a 3-2 win against Levante at the Santiago Bernabeu on Saturday.
Atletico Madrid came back from two goals and a man down to draw 2-2 at Levante on Saturday in their final La Liga game of the season.
Girona were left facing relegation from La Liga on Sunday after losing 2-1 in a dramatic encounter with fellow strugglers Levante.
Barcelona clinched back-to-back La Liga titles and their eighth in 11 years with a 1-0 win over Levante on Saturday.
Valencia stayed in the hunt for the final Champions League qualifying spot in La Liga with a rampant 3-1 win in a city derby at home to Levante.
Real Madrid's Gareth Bale came off the bench and coolly converted a penalty to secure a 2-1 win at Levante in La Liga.
Sevilla roared back to life from a slump in La Liga by thrashing Levante 5-0 at home on Saturday, scoring all their goals in the second half.
Barcelona will remain in the Copa del Rey after the RFEF's competition committee said on Friday it had rejected Levante's complaint.
However, Barca's status in a competition is unclear after Levante said they would file a complaint to the Spanish federation.
Antoine Griezmann proved to be Atletico Madrid's decisive figure yet again as the Frenchman struck the only goal in a 1-0 win at home to Levante.
Levante ran out shock 2-1 winners against Barcelona in the first leg of their Copa del Rey round-of-16 matchup on Thursday night.
In a weekend headlined by Liverpool's emphatic win over Manchester United, Lionel Messi and Cristiano Ronaldo continued to make new records.
Lionel Messi netted his first hat trick of the La Liga season and provided two assists in Barcelona's 5-0 win at Levante.