The Spartans hadn't won since December 29 against an NAIA foe, and had dropped eight straight.
Moore opened the game with a jump shot and two 3-pointers and USC Upstate (6-17, 1-7 Big South) never trailed, held Longwood to six points in the first 10 minutes and led 36-19 at the break. The Big South win was the first ever for the Spartans, who joined the conference this season.
The Spartans were 46 percent shooting from the floor, 28 of 61, and made 12 3-pointers. USC Upstate scored 20 points off 18 Longwood turnovers and had 19 assists.
No. 21 Colorado aims to stay perfect vs. Sacramento St.
After winning its first four games of the season by double-digit margins, No. 21 Colorado was taken to the last 6.2 seconds by Clemson on Tuesday night at Las Vegas in the MGM Main Event championship.
No. 25 Xavier hopes to be at full strength vs. Lipscomb
Xavier coach Travis Steele lamented the fact that his team "didn't show up" in the first 25 minutes of a five-point loss to Florida in the Charleston Classic finals on Sunday.
No. 15 Utah State draws hot-shooting Saint Mary's
No. 15 Utah State, which has its highest ranking in the AP poll since the 1970-71 season, will face one of the toughest tests of its season when it plays at hot-shooting Saint Mary's on Friday night in Moraga, Calif.