Georgia Southern (14-9, 6-4 Sun Belt Conference) shot 54 percent from the floor, 35 of 65, and drained 10 of 15 shots from behind the 3-point arc.
Brown, with three, and Jackson, with four, combined for the bulk of the Eagles 3-pointers. The pair nailed consecutive treys to break an early tie, giving Georgia Southern a 13-6 lead. The lead grew as large as 17 points for a 51-38 advantage at the half.
The Eagles opened the second half on a 9-3 pace, including 3-pointers by Calvin Wishart and Brown, and were up by as many as 25.
The Eagles, who remain in a tight bunch with the top five teams in the Sun Belt, scored the most points in a conference game since 2005.
The Ragin' Cajuns (13-10, 4-6) have lost their third in a row, giving up 104, 96 and 103 points.
The 'Fair Pay to Play Act' explained
Dan Murphy explains the landmark "Fair Pay to Play Act," which would allow financial compensation for collegiate athletes in California.
Villanova's Bryan Antoine yet to practice after shoulder surgery
Villanova star freshman Bryan Antoine underwent right shoulder surgery at the end of May and has yet to practice with the team.
Hot Board: Kentucky's Big Blue Madness attracts top prospects
Kentucky seizes the recruiting spotlight for this weekend's Big Blue Madness, with prospects Cade Cunningham and Paolo Banchero both visiting Lexington.